2003 -Degree in Medicine and Surgery, University of Milan, Milan, IT\r\n2007\r\nSpecialization in Radiodiagnostics, University of Milan, Milan, IT\r\n\r\nPROFESSIONAL EXPERIENCES\r\nFrom 2008 reader for the mammographic screening service organized by the ASL Milano2 (Certified Diploma in senology issued by ISPO, Florence, 2006\r\n\r\nPUBLICATION Collaboration on the research activities of the Radiology Unit of the IRCCS Policlinic San Donato , with 8 articles published in PubMed indexed journals with impact factor.\r\n
INTRODUCTION AND OBJECTIVES : The aim of this study is to check the possibility to use the test with micronuclei in saliva, for cases doubts, detected in screening for breast cancer\r\nMATERIAL AND METHODS It is been executed a bibliographic search on Pub Med (MEDLINE) ,Home Genetic Reference, for articles published from Jan 1, 2000 to Dec 31, 2016,for the keywords : \"micronuclei in exfoliated buccal cells in breast cancer “ The key words are used in the research in free text, and with cross –referencing method application. Another search it is been made for “MN in breast cancer “,from Jan1 2014 to today.\r\n RESULTS Five studies show that in buccal cells, in breast cancer , the amount of MN are significantly higher than compared to benign cases as in six studies for the detection of micronuclei in needle aspirates ductal,. Contrasting results are for MN in peripheral blood lymphocytes\r\nDISCUSSION . The micronuclei scoring can be used as a biomarker on fine needle aspiration cytology smears of breast cancer, while the tests in peripheral blood lymphocytes , have known reproducibility problems .The references show also,that is an increase of MN in exfoliated buccal mucosa cells test, May be interesting to apply the MN scoring in cases of doubt, according to functional BI-RADS category 3 (probably benign), and which are sent to a successive control\r\nCONCLUSIONS: it has verified that in buccal cells, in cases of breast cancer is significantly higher than the number of MN compared to benign cases, indicates the possibility of applying this technique in cases of doubt, in oral saliva
Dr. Salma AlDalla has completed her PhD at the age of 32 from The University of Manchester, UK. She has published 14 articles in reputed journals and has a work experience in Haematology & Blood Bank Laboratory. She has also published several papers in national and multinational journals. She is the senior of training courses of Haematology technicians in General Hospital Laboratory in Kuwait.
Hereditary spherocytosis (HS) is a heterogeneous group of hemolytic anemia caused by deficiency or dysfunction of red blood cell (RBC) cytoskeletal proteins. It is a common disorder located mostly in Caucasian population; most affected individuals have mild or only moderate hemolysis. In a few rare cases, the measurement of RBC membrane proteins is required to clarify the nature of the membrane disorder in absence of the family history. Patients with HS are at more risk of developing gallstones, whose prevention represents a major impetus for splenectomy in such patients. The main purpose of the study is to perform a mini review on the formation of gallstones in patients with hereditary spherocytosis. Hence, regular ultrasound and other diagnostic examinations are recommended for timely detection of any presence of gallstones in patients with HS.